Breast cancer stages

How are breast cancer stages determined?

The stages of breast cancer, ranging from 0 to IV, are based on a number of factors, such as the size of the tumor, whether cancer is found in the lymph nodes, and how far the cancer has spread. Your doctor will look at these factors to determine the stage of your breast cancer.

Early breast cancer

Stages I, IIA, and IIB (and some cancers of stage IIIA) are considered early breast cancer. At these stages, the cancer has not spread beyond the breast or the axillary lymph nodes (those under the arm).

early_stage
early_stage_mobile

Locally advanced breast cancer

Locally advanced breast cancer is a term used to describe large tumors in the breast. Types of locally advanced breast cancer—stage IIIA, IIIB, and IIIC—are distinguished by tumor size and location.

Stage IIIA locally advanced breast cancer

Stage IIIA

Stage IIIB

Stage IIIB locally advanced breast cancer
Stage IIIC locally advanced breast cancer

Stage IIIC

Stage IIIA locally advanced breast cancer
Stage IIIB locally advanced breast cancer
Stage IIIC locally advanced breast cancer

Stage IIIA

Stage IIIB

Stage IIIC

Metastatic breast cancer

Stage IV describes metastatic breast cancer, which is cancer that has spread from the breast to other parts of the body, such as the bones (bone metastases), or the liver, lungs, or brain (visceral metastases).

Sometimes, metastatic breast cancer is diagnosed at the first breast cancer diagnosis (called de novo metastatic breast cancer); at other times, metastatic breast cancer is diagnosed after early breast cancer treatment (referred to as recurrence).

STAGE4
STAGE4_mobile
Understanding breast cancer recurrence
Understanding breast cancer recurrence

Understanding recurrence

Cancer can return either in the same place as the original tumor or somewhere else in the body. Doctors use biopsies and other kinds of tests to gather information about the cancer, check for recurrence, and see if breast cancer cells have continued to spread. There are 3 types of breast cancer recurrence.

Local recurrence occurs in the breast where the cancer first started or in the skin and underlying tissues of the breast where the cancer first started. This type of breast cancer recurrence can happen even if you’ve had a mastectomy.

Regional recurrence occurs in the lymph nodes near the affected breast. These regional lymph nodes include nodes found under the arm and around the collarbone.

Distant recurrence occurs in other parts of the body, such as the bones, liver, lungs, or brain.

IMPORTANT SAFETY INFORMATION

  • You should not receive FASLODEX if you have had an allergic reaction to any of the ingredients in FASLODEX. Symptoms of an allergic reaction to FASLODEX may include: itching; swelling of your face, lips, tongue, or throat; trouble breathing
  • Before receiving FASLODEX, tell your healthcare provider about all of your medical conditions, including if you:

  • Have a low level of platelets in your blood or bleed easily. Especially tell your healthcare provider if you take a blood thinner medicine (anticoagulants)
  • Have liver problems
  • Are pregnant or plan to become pregnant, as FASLODEX can harm your unborn baby. Females who are able to become pregnant should use effective birth control during treatment with FASLODEX and for one year after the last dose. Tell your healthcare provider right away if you become pregnant or think you are pregnant while on FASLODEX
  • Are breast-feeding or plan to breast-feed. It is not known if FASLODEX passes into breast milk. Do not breast-feed during treatment with FASLODEX and for one year after the last dose. Talk to your healthcare provider about the best way to feed your baby during this time
  • FASLODEX is administered as a shot into the muscle of your buttock.

    FASLODEX may cause injection site related nerve damage. Call your healthcare provider if you develop any of the following symptoms in your legs following a FASLODEX injection: numbness; tingling; weakness.

    The most common side effects of FASLODEX include: injection site pain; nausea; muscle, joint, and bone pain; headache; tiredness; hot flashes; vomiting; loss of appetite; weakness; cough; shortness of breath, constipation; and increased liver enzymes.

Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all of the possible side effects with FASLODEX. For more information, ask your healthcare provider or pharmacist.

Approved Uses for FASLODEX

FASLODEX is a prescription medicine used to treat:

  • hormone receptor (HR)-positive breast cancer in women who have gone through menopause whose disease has spread after treatment with antiestrogen medicine, OR
  • HR-positive, human epidermal growth factor receptor 2 (HER2)‐negative breast cancer whose disease has spread to other parts of the body (metastatic) in combination with palbociclib in women with disease progression after hormonal therapy
  • When FASLODEX is used in combination with palbociclib, please also see the palbociclib Patient Information.

Please see FASLODEX Prescribing Information with Patient Information.

 
 
Read More

IMPORTANT SAFETY INFORMATION

  • You should not receive FASLODEX if you have had an allergic reaction to any of the ingredients in FASLODEX. Symptoms of an allergic reaction to FASLODEX may include: itching; swelling of your face, lips, tongue, or throat; trouble breathing
  • Before receiving FASLODEX, tell your healthcare provider about all of your medical conditions, including if you:

  • Have a low level of platelets in your blood or bleed easily. Especially tell your healthcare provider if you take a blood thinner medicine (anticoagulants)
  • Have liver problems
  • Are pregnant or plan to become pregnant, as FASLODEX can harm your unborn baby. Females who are able to become pregnant should use effective birth control during treatment with FASLODEX and for one year after the last dose. Tell your healthcare provider right away if you become pregnant or think you are pregnant while on FASLODEX
  • Are breast-feeding or plan to breast-feed. It is not known if FASLODEX passes into breast milk. Do not breast-feed during treatment with FASLODEX and for one year after the last dose. Talk to your healthcare provider about the best way to feed your baby during this time
  • FASLODEX is administered as a shot into the muscle of your buttock.

    FASLODEX may cause injection site related nerve damage. Call your healthcare provider if you develop any of the following symptoms in your legs following a FASLODEX injection: numbness; tingling; weakness.

    The most common side effects of FASLODEX include: injection site pain; nausea; muscle, joint, and bone pain; headache; tiredness; hot flashes; vomiting; loss of appetite; weakness; cough; shortness of breath, constipation; and increased liver enzymes.

Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all of the possible side effects with FASLODEX. For more information, ask your healthcare provider or pharmacist.

Approved Uses for FASLODEX

FASLODEX is a prescription medicine used to treat:

  • hormone receptor (HR)-positive breast cancer in women who have gone through menopause whose disease has spread after treatment with antiestrogen medicine, OR
  • HR-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer whose disease has spread to other parts of the body (metastatic) in combination with palbociclib in women with disease progression after hormonal therapy
  • When FASLODEX is used in combination with palbociclib, please also see the palbociclib Patient Information.