print_label | resize_label

Metastatic Breast Cancer Treatment Options

AZ
AZ

Women diagnosed with metastatic breast cancer have several treatment options to consider.

Many tests are used to evaluate a woman diagnosed with metastatic breast cancer. Your pathology report plays an important role in defining your treatment plan. It provides information you and your doctor need to make the best treatment choices for your particular diagnosis.

Your doctor will discuss your treatment options based on your particular cancer, test results, pathology reports, and previous treatments. Some of the therapies that may be options for women with metastatic breast cancer include the following:

Hormonal treatment

Chemotherapy

Biologically targeted therapy

Radiation therapy

Surgery

Hormonal treatment

Hormonal treatment is considered a systemic therapy, which means the medication travels in the bloodstream to affect or treat cancer cells. It has been prescribed to treat hormone receptor-positive metastatic breast cancer for many years. It may be used to reduce the growth or spread of breast cancer. If the cancer is found to be of the type that may be sensitive to estrogen, hormonal treatment may be able to keep estrogen from helping the cancer cells to grow and divide.

The presence of hormone receptors in the cancerous tumor is the best way to predict a woman's response to hormonal treatment for breast cancer. If it has not already been done, your doctor can do a test to determine the hormone receptor-status of your tumor.

The hormonal treatment you and your doctor decide is right for you will depend on a number of factors, such as whether you are premenopausal or postmenopausal. Ask your physician about these therapies.

A woman may have already received hormonal treatment following her initial diagnosis and treatment. FASLODEX is one hormonal treatment for hormone receptor-positive metastatic breast cancer in postmenopausal women whose breast cancer has returned or progressed following other antiestrogen therapy, such as tamoxifen. Click here to see how FASLODEX works.

Chemotherapy

Chemotherapy is the use of drugs that target and destroy rapidly dividing cells, including cancer cells. It can be used in metastatic breast cancer to shrink cancerous tumors and is sometimes used if it is believed that the breast cancer will not adequately respond to hormonal treatment. Chemotherapy is a systemic therapy.

Biologically targeted therapy

This term covers a range of treatments. These systemic therapies fight cancer by targeting specific features of cancer cells. They are often added to chemotherapy. For example, there are specific treatments that target breast cancer cells that make too much of a protein called HER2/neu. This targeted therapy can block the effects of the HER2/neu proteins, in which case the tumor cells are less able to grow.

Radiation therapy

Radiation therapy uses penetrating beams of high-energy waves or streams of particles to hinder the growth of or kill cancer cells. In metastatic disease, radiation is most commonly used to treat metastatic tumors in the brain, breast or chest wall or pain due to bone metastases. Radiation therapy is referred to as a local therapy because it treats a specific area of the body.

Surgery

Surgery is not commonly used in metastatic breast cancer but may be an option for some women. Surgery may be used in selected patients to remove painful breast tissue or metastases in the brain, spinal column, or lungs. Like radiation, surgery is considered a local therapy.

FASLODEX is a prescription medicine used to treat: hormone receptor (HR)-positive breast cancer in women who have gone through menopause whose disease has spread after treatment with antiestrogen medicine, OR HR-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer whose disease has spread to other parts of the body (metastatic) in combination with palbociclib in women with disease progression after hormonal therapy.

When FASLODEX is used in combination with palbociclib, please also see the palbociclib Patient Information.

IMPORTANT SAFETY INFORMATION: You should not receive FASLODEX if you have had an allergic reaction to any of the ingredients in FASLODEX. Symptoms of an allergic reaction to FASLODEX may include: itching; swelling of your face, lips, tongue, or throat; trouble breathing

Supporting women with metastatic breast cancer for over a decade.

Supporting women with metastatic breast cancer for over a decade.

 IMPORTANT SAFETY INFORMATION

  • You should not receive FASLODEX if you have had an allergic reaction to any of the ingredients in FASLODEX. Symptoms of an allergic reaction to FASLODEX may include: itching; swelling of your face, lips, tongue, or throat; trouble breathing
  • Before receiving FASLODEX, tell your healthcare provider about all of your medical conditions, including if you:

  • Have a low level of platelets in your blood or bleed easily. Especially tell your healthcare provider if you take a blood thinner medicine (anticoagulants)
  • Have liver problems
  • Are pregnant or plan to become pregnant, as FASLODEX can harm your unborn baby. Females who are able to become pregnant should use effective birth control during treatment with FASLODEX and for one year after the last dose. Tell your healthcare provider right away if you become pregnant or think you are pregnant while on FASLODEX
  • Are breast-feeding or plan to breast-feed. It is not known if FASLODEX passes into breast milk. Do not breast-feed during treatment with FASLODEX and for one year after the last dose. Talk to your healthcare provider about the best way to feed your baby during this time
  • FASLODEX is administered as a shot into the muscle of your buttock

    The most common side effects of FASLODEX include: injection site pain; nausea; muscle, joint, and bone pain; headache; tiredness; hot flashes; vomiting; loss of appetite; weakness; cough; shortness of breath, constipation; and increased liver enzymes.

    Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all of the possible side effects with FASLODEX. For more information, ask your healthcare provider or pharmacist.

Approved Uses for FASLODEX

FASLODEX is a prescription medicine used to treat:

  • hormone receptor (HR)-positive breast cancer in women who have gone through menopause whose disease has spread after treatment with antiestrogen medicine, OR
  • HR-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer whose disease has spread to other parts of the body (metastatic) in combination with palbociclib in women with disease progression after hormonal therapy

When FASLODEX is used in combination with palbociclib, please also see the palbociclib Patient Information.

Please see FASLODEX Prescribing Information with Patient Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

This site is intended for US consumers only.

The information on this Web site should not take the place of talking with your doctor or health care professional. If you have any questions about your condition, or if you would like more information about FASLODEX, talk to your doctor or pharmacist. Only you and your health care professional can decide if FASLODEX is right for you.