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FASLODEX Side Effects

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The safety of FASLODEX has been evaluated in clinical studies. As with any medication, you may experience side effects when taking FASLODEX, so it is important to be prepared. Click here to get helpful questions to ask your doctor.

During your treatment with FASLODEX, you may experience side effects. If you are concerned about any symptoms you may be experiencing, you should contact your doctor’s office right away.

Most common side effects

In a clinical trial, commonly reported side effects seen with FASLODEX were injection site pain, nausea, muscle, joint, and bone pain, headache, tiredness, hot flashes, vomiting, loss of appetite, weakness, cough, constipation, shortness of breath, and increased liver enzymes

0.6% of patients receiving FASLODEX 500 mg and 0.8% of patients receiving FASLODEX 250 mg withdrew from treatment due to drug-related side effects

Because FASLODEX is metabolized, or broken down, primarily in the liver, a monthly dose of 250 mg is recommended for patients with moderate liver problems.

FASLODEX was not studied in patients with severe liver problems.

Because FASLODEX is administered directly into the muscle, you should tell your doctor if you have a blood disorder or are on anticoagulants (sometimes called blood thinners).

Talk to your doctor to see if FASLODEX is right for you 

FASLODEX is a prescription medicine used to treat: hormone receptor (HR)-positive breast cancer in women who have gone through menopause whose disease has spread after treatment with antiestrogen medicine, OR HR-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer whose disease has spread to other parts of the body (metastatic) in combination with palbociclib in women with disease progression after hormonal therapy.

When FASLODEX is used in combination with palbociclib, please also see the palbociclib Patient Information.

IMPORTANT SAFETY INFORMATION: You should not receive FASLODEX if you have had an allergic reaction to any of the ingredients in FASLODEX. Symptoms of an allergic reaction to FASLODEX may include: itching; swelling of your face, lips, tongue, or throat; trouble breathing

Supporting women with metastatic breast cancer for over a decade.

Supporting women with metastatic breast cancer for over a decade.

 IMPORTANT SAFETY INFORMATION

  • You should not receive FASLODEX if you have had an allergic reaction to any of the ingredients in FASLODEX. Symptoms of an allergic reaction to FASLODEX may include: itching; swelling of your face, lips, tongue, or throat; trouble breathing
  • Before receiving FASLODEX, tell your healthcare provider about all of your medical conditions, including if you:

  • Have a low level of platelets in your blood or bleed easily. Especially tell your healthcare provider if you take a blood thinner medicine (anticoagulants)
  • Have liver problems
  • Are pregnant or plan to become pregnant, as FASLODEX can harm your unborn baby. Females who are able to become pregnant should use effective birth control during treatment with FASLODEX and for one year after the last dose. Tell your healthcare provider right away if you become pregnant or think you are pregnant while on FASLODEX
  • Are breast-feeding or plan to breast-feed. It is not known if FASLODEX passes into breast milk. Do not breast-feed during treatment with FASLODEX and for one year after the last dose. Talk to your healthcare provider about the best way to feed your baby during this time
  • FASLODEX is administered as a shot into the muscle of your buttock.

    FASLODEX may cause injection site related nerve damage. Call your healthcare provider if you develop any of the following symptoms in your legs following a FASLODEX injection: numbness; tingling; weakness.

    The most common side effects of FASLODEX include: injection site pain; nausea; muscle, joint, and bone pain; headache; tiredness; hot flashes; vomiting; loss of appetite; weakness; cough; shortness of breath, constipation; and increased liver enzymes.

    Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all of the possible side effects with FASLODEX. For more information, ask your healthcare provider or pharmacist.

Approved Uses for FASLODEX

FASLODEX is a prescription medicine used to treat:

  • hormone receptor (HR)-positive breast cancer in women who have gone through menopause whose disease has spread after treatment with antiestrogen medicine, OR
  • HR-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer whose disease has spread to other parts of the body (metastatic) in combination with palbociclib in women with disease progression after hormonal therapy

When FASLODEX is used in combination with palbociclib, please also see the palbociclib Patient Information.

Please see FASLODEX Prescribing Information with Patient Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

If you would like additional information regarding AstraZeneca products, please contact the Information Center at AstraZeneca in the United States at 1-800-236-9933, Monday through Friday, 8 AM to 6 PM ET, excluding holidays.

This site is intended for US consumers only.

The information on this Web site should not take the place of talking with your doctor or health care professional. If you have any questions about your condition, or if you would like more information about FASLODEX, talk to your doctor or pharmacist. Only you and your health care professional can decide if FASLODEX is right for you.