Frequently Asked Questions

• I’m concerned about the side effects of FASLODEX 500 mg versus 250 mg. Will doubling the dose double the side effects?
• How can I get my questions about reimbursement answered?
• What is the NDC code for ordering?
• How is FASLODEX 500 mg supplied?
• If I use a 250-mg dose for a patient with moderate hepatic impairment, how should I store the FASLODEX 2 x 5 mL pack?

I’m concerned about the side effects of FASLODEX 500 mg versus 250 mg. Will doubling the dose double the side effects?

A: Although the dose was double, the Study 1 (CONFIRM) trial demonstrated that FASLODEX 500 mg had a safety profile comparable to 250 mg in terms of the most commonly reported adverse events.² In the Study 1 (CONFIRM) trial, the most common adverse reactions reported for patients treated with FASLODEX 500 mg were injection site pain (11.6% of patients), nausea (9.7% of patients) and bone pain (9.4% of patients); the most frequently reported adverse reactions in the FASLODEX 250 mg group were nausea (13.6% of patients), back pain (10.7% of patients), and injection site pain (9.1% of patients).¹

How can I get my questions about reimbursement answered?

A: You can call our AstraZeneca Reimbursement Services, a team of reimbursement specialists, to assist your office with coding, coverage, and payment inquiries. The phone number is 1-877-674-7140, Monday through Friday, 8:00 AM to 6:00 PM ET.

What is the NDC code for ordering?

A: You may order the FASLODEX 500-mg (2 x 5-mL) pack through your wholesaler. The NDC code is NDC 0310-0720-10.¹ If you have questions and would like to have an AstraZeneca representative contact you, you may Request a Rep.

How is FASLODEX 500 mg supplied?

A: FASLODEX is now supplied as two 5-mL clear neutral glass barrels, each containing 250 mg/5 mL of fulvestrant solution for intramuscular injection and fitted with a tamper-evident closure.¹ The syringes are presented in a tray with a polystyrene plunger rod and safety needles (SafetyGlide™) for connection to the barrel.¹

If I use a 250-mg dose for a patient with moderate hepatic impairment, how should I store the FASLODEX 2 x 5 mL pack?

A: Immediately store the other 5-mL syringe as directed in the Prescribing Information— REFRIGERATE, 2°-8°C (36°-46°F). TO PROTECT FROM LIGHT, STORE IN ORIGINAL CARTON.¹