Metastatic (Stage IV) Breast Cancer Glossary

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

A

Adjuvant therapy: Additional cancer treatment given after the primary treatment to lower the risk that the cancer will come back. Adjuvant therapy may include chemotherapy, radiation therapy, hormonal therapy, targeted therapy, or biological therapy.

Antiestrogen: Medication that is used to treat breast cancers that depend on estrogen for growth.

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C

Chemotherapy: Treatment with drugs that attack and kill rapidly growing cancer cells and some normal cells.

Clinical trial: A medical study that tests the safety and effectiveness of a drug or intervention in people.

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D

De novo: The first occurrence of cancer found.

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E

Estrogen: A female hormone; one of the hormones that can help some breast cancer tumors grow.

Estrogen receptor: A protein associated with cells. The hormone estrogen will bind to the receptors inside the cells and may cause the cells to grow.

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H

Hormonal treatment (therapy): In breast cancer, using drugs to block the effects or production of estrogen.

Hormone receptor positive: Refers to cells that have a receptor for estrogen or progesterone. Cancer cells that are hormone receptor-positive can grow when estrogen or progesterone attaches to receptors.

Hormones: Substances produced by organs or cells in your body that affect bodily processes. Estrogen and progesterone are examples.

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I

Intramuscular injection: An injection given into the muscle.

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L

Loading dose: A large initial dose of a substance or a series of such doses given to rapidly achieve a therapeutic concentration in the body.

Locally advanced breast cancer: Cancer that has spread from where it started in the breast to nearby tissue or lymph nodes, but not to other parts of the body.

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M

Metastatic breast cancer: Also referred to as stage IV breast cancer; cancer that has spread from the breast to other parts of the body, such as the bones, liver, lungs, or brain.

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P

Postmenopausal: Refers to the time after menopause. Menopause is when you have permanently stopped having menstrual periods.

Progression-free survival: In a clinical trial, the time between randomization and the earliest of progression or death from any cause.

Progesterone: A hormone that is important in menstruation and fertility. It may affect the growth of some breast cancers (those that are determined to be progesterone receptor positive).

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S

Soft tissue: Refers to muscle, fat, fibrous tissue, blood vessels, or other supporting tissue of the body.

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V

Visceral: Soft internal organs of the body, including the lungs, the heart, and the organs of the digestive, excretory, reproductive, and circulatory systems.

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FASLODEX is a prescription medicine used to treat hormone receptor-positive metastatic breast cancer in women who have gone through menopause whose disease has spread after treatment with antiestrogen medicine.

IMPORTANT SAFETY INFORMATION: You should not receive FASLODEX if you have had an allergic reaction to any of the ingredients in FASLODEX. Symptoms of an allergic reaction to FASLODEX may include itching, swelling of your face, lips, tongue, or throat, or trouble breathing.

Click here for additional safety information.