How FASLODEX works

hormone receptor-positive breast cancer is a type of breast cancer in which cells need the hormone estrogen to grow. The hormone estrogen will bind to the receptors inside the cells and may cause the cells to grow.

Given by intramuscular (IM) injection once a month, FASLODEX works by attaching to estrogen receptors, which blocks estrogen from binding. FASLODEX causes the estrogen receptor to change shape and not work as well. In addition, FASLODEX causes a decrease (downregulation) in the number of estrogen receptors.

In clinical trials, FASLODEX was found to be effective when tamoxifen no longer worked. Watch the video to learn more about how FASLODEX works.

See how FASLODEX works

Video describes how FASLODEX fulvestrant injection works. FASLODEX is a hormonal treatment for postmenopausal women with hormone receptor-positive metastatic breast cancer. Video shows that some breast cancer tumors need estrogen to grow. FASLODEX is an antiestrogen that blocks estrogen from attaching to estrogen receptors in tumors in which the estrogen receptor status is estrogen receptor positive. FASLODEX fulvestrant injection is a hormonal therapy used to treat breast cancer recurrence. It is for advanced breast cancer patients with locally advanced stage III or stage IV metastatic breast cancer.

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To find out if your tumor may respond to FASLODEX, your doctor can do a test to determine if your tumor is hormone receptor positive. Breast cancer tumors are hormone receptor positive in more than 60% of postmenopausal women.

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