Hormone receptors and metastatic breast cancer
The cells of metastatic breast cancers may have receptors for estrogen and progesterone. When they do, the metastatic breast cancer is said to be hormone receptor-positive. When breast cancers are estrogen receptor positive, estrogen may contribute to the growth and spread of the cancer.
Hormonal treatments are often used to treat hormone receptor-positive breast cancer. They work by blocking the effects of estrogen on breast cancer cells, or by reducing the amount of estrogen produced by the body.
How estrogen affects breast cancer
Estrogen does not cause breast cancer, although it may promote the growth of some tumors. Here's how certain breast cancer cells live and grow with the help of estrogen.
Estrogen finds a specialized receiver in a cell, called a receptor. Estrogen attaches itself to estrogen receptors. These receptors take the estrogen and bring it into the center of the cancer cell (nucleus) so that estrogen can give the signal for the tumor to grow.
Result: cancer cells grow and divide to form more cells.
FASLODEX works by interacting with hormone receptors.
Learn more about FASLODEX and see how it works
Metastatic breast cancer is generally not curable, but is considered treatable.
Learn more about metastatic breast cancer treatments
FASLODEX is a prescription medicine used to treat hormone receptor-positive breast cancer in women who have gone through menopause whose disease has spread after treatment with antiestrogen medicine.
IMPORTANT SAFETY INFORMATION: You should not receive FASLODEX if you have had an allergic reaction to any of the ingredients in FASLODEX. Symptoms of an allergic reaction to FASLODEX may include itching, swelling of your face, lips, tongue, or throat, or trouble breathing.
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